Anti aging research show Vitamin C may stop premature aging
Anti aging research is aimed at life extension and refers to attempts to slow down or reverse the natural process of aging. The main goals are to extend both the maximum and average lifespan. Many anti aging products and treatments are suggested to the public with the promise of life extension; most of them are not supported by anti aging research.
Aging is caused by accumulation of damage to molecules leading eventually to damage to cells, tissue and organs. The maximum life span for humans is in excess of 120 years, whereas the maximum lifespan of a mouse, commonly used as a model in research on anti aging, is about four years. Genetic differences between humans and mice that may account for these different aging rates include efficiency of DNA repair, types and quantities of antioxidant, enzymes, and different rates of free radical production. Despite these differences mutant mice are commonly used in anti aging research for approval of anti aging products and technologies.
Vitamin C is very well known antioxidant and is recommended as anti aging product. It is known to boosts and strengthens the immune system. A new anti aging research published by Canadian scientists have discovered a good evidence on mutant mice that may reveal that Vitamin C is a great anti aging tool for a certain type of age-related disease.
The study published in the FASEB Journal has found that increased vitamin C intake on a daily basis can stop and possibly reverse signs of aging associated with Werner’s syndrome, a disease that causes accelerated aging and age-related diseases. The Werner's syndrome, a disease that is caused by a defect of the WRN (Werner) gene and the WRN protein and is responsible for accelerated aging and age-related diseases in humans as young as those in their 20s. Those who suffer from it develop age-related diseases and generally pass away before they reach their 50s.
For the purposes of their research, the experts treated both normal mice and mutant mice with WRN gene with vitamin C-enriched drinking water. Before the experiment, the mice with the Werner's syndrome gene were fat, had diabetes, developing cardiovascular disease and cancer. However, once treated with the vitamin C, the mutant mice turned out to be as healthy as the normal mice and lived a normal lifespan. The researchers observed that vitamin C also improved how the mice stored and burned fat, lowered tissue inflammation and decreased oxidative stress in the WRN mice. The healthy mice did not appear to gain any benefit from vitamin C.
Dr. Michel Lebel, one of the study's lead authors say "Our study clearly indicates that a healthy organism or individuals with no health problems do not require a large amount of vitamin C in order to increase their lifespan, especially if they have a balanced diet and they exercise".
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